Cytohistopathological Correlation of 884 Cervical Pap Smears as Bethesda System 2014: A Hospital-Based Study

Cervical carcinoma is most common in Indian women of which Rural are predominantly affected. The etiological factor human papillomavirus (HPV ). present study aims to assess the diagnostic accuracy, sensitivity, specificity, and different patterns cervical Pap smears by comparing histological findings. index a retrospective cross-sectional analytical study. data was collected at pathology department from May 2017 December 2019 according hospital ethical protocol. received underwent staining. A total 884 were satisfactory included age enrolled 46.4 ± 9.7 years. 800 reported as negative for intraepithelial lesion (NILM), 84 abnormal. Abnormal pap 64 (7.1%) atypical squamous cell-undetermined significance (ASC-US), 9 (1.01%) low-grade (LSIL), 5 (0.56%) high-grade cannot be ruled out (ASC-H), 3 cases (0.33%) high grade (HSIL), 2 (0.22%) glandular cell-not specific otherwise (AGC-NOS) 1 case (0.11%) cell carcinoma. cytohistological correlation found 56 patients, including 41.07% with chronic cervicitis, 26.75% cervicitis metaplasia, 5.35% polyps, 3.57% CIN-1, 14.28% situ, 7.14% (keratinizing), 1.78% (non-keratinizing) patients. Cytohistological revealed sensitivity (83.33%), specificity (94.73%), PPV (88.23%), NPV (92.3%) accuracy (91.07%). test cost-effective, almost sensitive, accurate histology screening lesions.